Endocrine Abstracts

Introduction: Adrenal gland involvement can be seen in about 25% of lymphomas. However, primary adrenal lymphomas (PAL) are rare. The most common is diffuse large B-cell lymphoma (DLBCL). It is seen usually after the age of 60 years as bilateral, large masses.Case report: A 64-year-old woman with a complaint of abdominal pain was referred to our clinic after bilateral surrenal masses were detected upon abdominal ultrasonography (USG) and computed tomogra...

Introduction: Adrenocortical carcinoma (ACC) is a very rare tumor. The mean age at onset is between 40 and 50 years. Patients with nonfunctioning ACC report symptoms of abdominal discomfort or back pain due to the large tumor size. Surgery for ACC should be performed by an expert surgeon.Case: A 29-year-old patient with 25 weeks of pregnancy admitted at our clinic with right side pain. 10×11 cm solid mass on right adrenal gland was detected by ultra...

Introduction: Thyrotropinomas are usually considered when the TSH level is inappropriately elevated or normal in a hyperthyroid patient with increased serum T4 levels, regardless of the presence of visible tumor on imaging. The prevalence of these adenomas, which account for 0.5–3% of all pituitary tumors has been estimated to be around one case per million. Most thyrotroph adenomas are large and invasive at diagnosis, and present with signs and symptoms of an ...

Purpose: The purpose of this study was to evaluate the relation polycystic ovarian syndome (PCOS) and the thiol/disulfide balance, used as a marker of oxidative stress, by measuring that exchange using a novel technique.Material/methods: Fourty nine subjects diagnosed with PCOS and 44 healthy were included in the study. Thiol/disulfide homeostasis concentrations were measured by a newly developed method. After native thiol, total thiol and disulfide leve...

Introduction and purpose: More than 90% of differentiated thyroid cancers are papillary thyroid cancer (PTC). Lymph node metastasis is common in PTC and has been reported to have no effect on prognosis. The risk of cervical metastasis is high in the presence of clinicopathologic factors including extrathyroidal extension, multifocality and lymphovascular invasion. In this study, it was aimed to evaluate the clinicopathological features of lymph node metastasis development....

Aims: We aimed to determine the irisin level in patients with type 1 diabetes mellitus (T1DM) and to examine the relation of irisin level with inflammation and autoimmunity.Methods: This study included 35 cases diagnosed with T1DM and 36 healthy volunteers. Anti-glutamic acid decarboxylase (Anti-GAD), islet cell antibody (ICA), insulin autoantibody levels of the patients have been measured at the time they were included in the study and were recorded fro...

In the present study, we aimed to investigate the efficiency of ultrasound-guided fine-needle aspiration biopsy in our clinic. Totally, 701 patients followed at Department of Endocrinology, Faculty of Medicine, Eskisehir Osmangazi University with nodular thyroid disorder were included in this study during January 2000 and January 2011. Ultrasound-guided thyroid fine-needle aspiration biopsy was performed in these 701 cases at Interventional Radiology Department. Throid nodules...

Introduction: Gastrointestinal tract is one of the most affected systems in hypothyroidism. The most plausible mechanism in the pathogenesis is the development of interstitial edema subsequent to accumulation of glycosaminoglycans. Despite decreased esophageal emptying, prolonged esophageal and gastric transit time has been indicated in previous reports, the mechanism of thyroid hormones activity on the gastrointestinal system is not yet fully understood. To our knowledge, thi...

Introduction: Vitamin D deficiency has become a major public health problem. It’s known that the effects of vitamin D are made by its receptors. VDR gene polymorphisms in susceptibility to different diseases demonstrated in many studies. The polymorphisms of VDR are ApaI, TaqI, FokI, and BsmI. BsmI is the most extensively studied polymorphism. In our study, the aim is to show the frequency of VDR BsmI gene polymorphisms and to show the relationship between polymorphisms a...

Introduction: Oncocytic (Hurthle cell) carcinoma is consisted of <5% of thyroid cancer but most metastasizing cancer type among differentiated thyroid cancer. We presented an oncocytic carcinoma with sternum metastasis.Case: A 68-year-old women admitted to endocrinology policlinic with complaint of a mass in her neck. She was diagnosed hyperthyroidism and she was using thionamid for 6 months. Her medical history revealed hypertension for 3 years and ...